Answer by Craig Hicks for What are the correct permissions for the .gnupg enclosing folder? gpg: WARNING: unsafe enclosing directory permissions on configuration file

These two lines will set the permissions separately and correctly for directories and files:

find ~/.gnupg -type d -exec chmod 700 {} \;
find ~/.gnupg -type f -exec chmod 600 {} \;

assuming ownership is already set correctly.

Note it does not change permissions on the sockets S.gpg-agent*. (Only the new gpg v2 involves sockets, the old gpg v1 doesn't).